ABSTRACTS AND POSTERS

2018

Murray et al. A prospective cohort study in colorectal cancer assessing the relationship between post-surgery detection of methylated BCAT1 or IKZF1 ctDNA and risk for residual disease and survival. ASCO Annual Meeting, 2018.

Online abstract publications at ASCO June 2018, “Detection of ctDNA biomarkers post resection and relationship to recurrent disease in colorectal cancer patients”.

Symonds et al. Circulating Tumor DNA to Assess Characteristics of Colorectal Cancer and Completeness of Surgical Resection. Digestive Disease Week Annual Meeting, 2018.

Young et al. Methylated circulating tumor-derived DNA for detection of colorectal cancer – relationship of methylated BCAT1 or IKZF1 to tissue expression and comparison with FIT. Early Detection Research Network Annual Meeting, 2018.

Symonds et al. Specificity of methylated BCAT1 and IKZF1 for colorectal cancer. ASCO GI, 2018.

2016

Symonds et al. Methylated BCAT1 and IKZF1 DNA in tissue and plasma from colorectal cancer cases. Presented at ASCO GI Symposium, 2016.

Pedersenet al. A novel 2-gene blood test for colorectal cancer recurrence. Presented at ASCO GI Symposium, 2016.

2015

Baker et al. Detection of variable methylation patterns improves sensitivity of a colorectal cancer blood test. Digestive Disease Week, 2015.

Symonds et al. Improving participation rates in community-based colorectal cancer screening – role of a blood test. Digestive Disease Week, 2015.

Symonds et al. Methylated BCAT1 and IKZF1 DNA in plasma as novel biomarkers for colorectal cancer recurrence. Digestive Disease Week, 2015.

Symonds et al. Comparison of a methylated two-gene (BCAT1-IKZF1) blood test to FIT for detection of colorectal neoplasia. Digestive Disease Week, 2015.

Mangira et al. The morphological features of colorectal tumors that are associated with the appearance of methylated DNA in plasma. Digestive Disease Week, 2015.

Asia-Pacific Journal of Clinical Oncology, Vol. 10, Issue Suppl. S9, p211-212. DOI: 10.1111/ajco.12332

2014

Baker et al. Detection of variable methylation patterns improves colorectal cancer blood test sensitivity. AGW, 2014.

Symonds et al. A methylated DNA blood test for colorectal cancer screening returns a lower false positivity rate than a faecal immunochemical test in people with benign bleeding conditions. AGW, 2014.

Mangira et al. Appearance of tumor-associated methylated DNA in plasma correlates with colorectal tumour invasion. Flinders Centre for Innovation in Cancer, 2014.

Baker et al. Method validation of a laboratory–developed blood test for colorectal cancer. Combio2014 Conference, 2014.

Young. Evaluation of a 2-gene (IKZF1 and BCAT1) DNA blood test for detection of colorectal cancer. Digestive Disease Week, 2014.

Redwood et al. Comparison of Fecal Occult Blood Tests for Colorectal Cancer Screening in an Alaska Native Population With High Prevalence of Helicobacter pylori Infection, 2008-2012. Prev Chronic Dis 2014;11:130281.

Mitchell et al. Colorectal cancer methylation biomarkers. Keystone Symposia Conference – Cancer Epigenetics, 2014.

2013

Baker et al. Clinical evaluation of a novel duplexed 2-gene DNA methylation blood test for colorectal cancer. Lorne Genome Conference, 2013.

Rand et al. Development of non-bisulphite-based assays for colorectal cancer DNA methylation markers. Gordon Research Conference – Cancer Genetics & Epigenetics, 2013.

2012

Pedersen. Novel methylation DNA biomarkers for colorectal neoplasia: From tissue to blood.  WEO Colorectal Cancer Screening Committee Meeting, 2012.

Pedersen. Discovery and validation of a novel DNA methylation biomarker for colorectal cancer with application to blood testing.  Digestive Disease Week, 2012.

Baker et al. Clinical Evaluation of a novel 2-gene methylation blood test for colorectal cancer. Australian Gastroenterology Week, 2012.

2011

Thomas et al. Plasma Testing of Gene Expression Biomarkers for Colorectal Neoplasia discovered in Neoplastic Colorectal Tissue. Digestive Disease Week (AGA), 2011.

2009

LaPointe et al. Biomarkers with high sensitivity and specificity for colorectal adenomas and carcinomas. Digestive Disease Week (AGA), 2009.

Pedersen et al. A novel colorectal neoplasia gene (CRNG) with high sensitivity and specificity for both adenomas and carcinomas. Digestive Disease Week (AGA), 2009.

Pedersen et al. Alternative splicing of S100A11 in colorectal adenomas and carcinomas. Digestive Disease Week (AGA), 2009.

Moynihanet al. Upregulation of mesolthelin, RegIV, and transcobalamin in colon adenomas and cancer. Digestive Disease Week (AGA), 2009.

2006

Wilson et al. Associative gene networks from microarray data in the normal colon. CSIRO Mathematical and Informational Sciences Annual Divisional Conference, 2006.

LaPointe et al. Mapping gene expression along the anterior-posterior axis of the adult human colon. Digestive Disease Week (AGA), 2006.

2005

LaPointe et al. Comparison of classification methodologies to discover biomarkers from gene expression data. Australian Microarrays Conference (AMATA), 2005.

Kiiveri et al. Canonical Variate Analysis and Microarrays. Australian Microarrays Conference (AMATA), 2005.

LaPointe et al. Comparison of machine learning techniques to identify biomarkers for colorectal cancer in publicly available data. International Society of Computational Biology, 2005.

LaPointe et al.. Identification of colorectal cancer biomarkers using publicly available gene expression data. Digestive Disease Week (AGA), Chicago, 2005.

2004

Young et al. A quantifiable fecal immunochemical test (FIT) for hemoglobin facilitates balancing sensitivity with specificity when screening for colorectal cancer. European Gastroenterology Week, 2004.

Smith et al. A quantifiable faecal immunochemical test (FIT) for haemoglobin balancing sensitivity with specificity when screening for colorectal cancer. J. Gastro Hepatology 19(Suppl): A195, 2004.

Smith et al. A quantifiable faecal immunochemical test (FIT) for haemoglobin balancing sensitivity with specificity when screening for colorectal cancer. Gastroenterology 126(Suppl), 2004.

2003

LaPointe et al. Analysis of mRNA expression profiles in colorectal adenomas using k-nearest neighbor cluster analysis. Digestive Disease Week (AGA), 2003.

LaPointe et al. Selecting for diagnostic colonoscopy by quantifiable fecal immunochemical tests. Gastroenterology, Supplement to 124(4), 2003.

2000

Sinatra et al. Faecal hemoglobin measurement in colorectal neoplasia. J Gastro Hepatology, Supplement to 15, 2000.

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